My brother has been teaching ________ he was 21 years old.

A．when B．if C．for D．since

D

解析試題分析：主句用的是現(xiàn)在完成時態(tài)。since，自從……（到現(xiàn)在）現(xiàn)在完成時的標志詞。句意：我的弟弟自從21歲就一直在教學。
考點：考查連詞。

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